Thermo Fisher Scientific TrkA Recombinant Rabbit Monoclonal Antibody (2A5)
TrkA 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 Immunocytochemistry에 적합. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태. 신경 성장 인자 수용체 연구에 유용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:5,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2A5 |
| Immunogen | A synthesized peptide derived from human TrkA (700–796aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898226 |
Product Specific Information
This antibody has been tested in direct ELISA.
Target Information
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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