Thermo Fisher Scientific TPT1 Recombinant Rabbit Monoclonal Antibody (10A9)
TPT1 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, IHC, ICC, IP 등 다양한 실험에 사용 가능. 인간과 생쥐 시료에 반응하며, 고순도 친화 크로마토그래피 정제. PBS 기반 완충액에 보관되며 -20°C 이하에서 안정적 저장 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:20–1:200 |
| Immunoprecipitation (IP) | 1:200–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10A9 |
| Immunogen | A synthesized peptide derived from human TCTP (TPT1, UniProt ID: P13693-1, antigen range: 51–65, length: 172 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.16 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898230 |
Product Specific Information
This antibody has been tested in direct ELISA.
Target Information
TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium-binding proteins. It is localized in the cytoplasm and widely expressed, functioning as a transcriptional activator, calcium transporter, histamine inducer, and anti-apoptotic caspase-3 inhibitor.
TPT1 acts as a cytokine-like molecule that triggers the release of histamine, IL-4, and IL-13 from basophils, as well as IL-8 secretion and calcium responses in eosinophils.
It plays a key role in allergic diseases and may be involved in neurodegenerative disorders such as Alzheimer’s disease and Down syndrome due to its broad distribution in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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