Thermo Fisher Scientific FKBP5/FKBP51 Polyclonal Antibody
FKBP5/FKBP51 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 IHC-P에 적합합니다. 인간 시료에 반응하며, FKBP5 단백질의 407-457 아미노산 영역을 면역원으로 사용했습니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 407 and 457 of human FK506 binding protein 5 (51 kDa FK506-binding protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Chimpanzee, and Northern white-cheeked gibbon
Target Information
FKBP5 is a member of the immunophilin protein family involved in immunoregulation and basic cellular processes such as protein folding and trafficking.
It functions as a cis-trans prolyl isomerase that binds to FK506 and rapamycin, mediating calcineurin inhibition.
FKBP5 interacts with mature hetero-oligomeric progesterone receptor complexes, along with the 90 kDa heat shock protein and P23 protein.
The FKBP5 gene has multiple polyadenylation sites, and alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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