
Thermo Fisher Scientific WIPI1 Polyclonal Antibody
WIPI1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot과 IHC에 사용 가능. 자가 합성 펩타이드(aa 350–400)를 면역원으로 제작. 사람 시료에 반응하며, 자가포식 연구 및 단백질 수송 경로 분석에 적합. 동결건조 형태로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 350–400 of human WIPI1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term. For long-term storage, keep at −20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide shares 91% identity with mouse sequence.
- Specificity: WIPI1.
Target Information
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is involved in autophagy and may regulate protein trafficking in recycling pathways.
It contains three WD repeats forming a 7-bladed propeller structure with a conserved motif facilitating protein interactions.
WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network.
It is ubiquitously expressed, with highest levels in heart, testis, placenta, pancreas, and skeletal muscle.
Upregulation in various tumors suggests a role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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