Thermo Fisher Scientific APOBEC3B Polyclonal Antibody
Thermo Fisher Scientific의 APOBEC3B Polyclonal Antibody는 인간 APOBEC3B 단백질을 인식하는 토끼 다클론 항체입니다. Western blot과 ELISA에 적합하며, 핵 내 단백질 검출에 사용됩니다. 고순도 친화 크로마토그래피 정제 및 안정적 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 151–250 of human APOBEC3B (NP_004891.5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.88 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914792 |
Product Specific Information
- Positive test controls: HeLa, U-251MG, MCF7
- Subcellular localization: Nucleus
Immunogen sequence:
EEFAYCWENF VYNEGQQFMP WYKFDENYAF LHRTLKEILR YLMDPDTFTF NFNNDPLVLR RRQTYLCYEV ERLDNGTWVL MDQHMGFLCN EAKNLLCGFY
Target Information
This gene belongs to the cytidine deaminase gene family. It is part of a cluster of seven related genes or pseudogenes on chromosome 22, likely arising from gene duplication. Members of this cluster encode proteins related to the C-to-U RNA-editing cytidine deaminase APOBEC1. These proteins may function as RNA editing enzymes and play roles in growth or cell cycle control.
A hybrid gene results from deletion of approximately 29.5 kb between APOBEC3B and APOBEC3A, producing a combined allele with the APOBEC3A promoter and coding region, and the APOBEC3B 3′ UTR. Two transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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