Thermo Fisher Scientific FCAR Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Positive test controls include: 293T.
The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein.

Immunogen sequence:
LMIIKNSTYR EIGRRLKFWN ETDPEFVIDH MDANKAGRYQ CQYRIGHYRF RYSDTLELVV TGLYGKPFLS ADRGLVLMPG ENISLTCSSA HIPFDRFSLA KEGELSLPQH QSGEHPANFS LGPVDLNVSG IYRCYGWYNR SPYLWSFPSN ALELVVTDSI HQDYTTQNLI RMAVAGLVLV ALLAILVENW HSHTALNKEA SADVAEPSWS QQMCQPGLTF ARTPSVCK

Target Information

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA.
The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens.
It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators.
Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.