Thermo Fisher Scientific FCAR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD89 (FCAR),uniProtId:P24071-1,ncbiNodeId:9606,antigenRange:60-287,antigenLength:287,antigenImageFileName:PA5-121219_CD89_FCAR_P24071-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121219_CD89_FCAR_P24071-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.66 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914791

Product Specific Information

Positive test controls include: 293T. The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein.

Immunogen sequence: LMIIKNSTYR EIGRRLKFWN ETDPEFVIDH MDANKAGRYQ CQYRIGHYRF RYSDTLELVV TGLYGKPFLS ADRGLVLMPG ENISLTCSSA HIPFDRFSLA KEGELSLPQH QSGEHPANFS LGPVDLNVSG IYRCYGWYNR SPYLWSFPSN ALELVVTDSI HQDYTTQNLI RMAVAGLVLV ALLAILVENW HSHTALNKEA SADVAEPSWS QQMCQPGLTF ARTPSVCK

Target Information

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.