Thermo Fisher Scientific CD8B (Cytotoxic/Suppressor T-Cell Marker) Monoclonal Antibody (CBB/1595)
CD8B 단백질을 인식하는 단클론 항체로, 세포독성 및 억제 T세포 표지 연구에 적합합니다. 소, 염소, 양에 반응하며, ELISA 등 다양한 면역분석에 활용 가능합니다. 단백질 A/G 정제, 무보존제 PBS 용액 형태로 제공됩니다.
- 카탈로그번호
- 926-MSM2-P1ABX
- 판매단위
- pk
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Goat, Sheep |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CBB/1595 |
| Immunogen | Antibody was raised against bovine CD8b. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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