Thermo Fisher Scientific RRM1 Monoclonal Antibody (OTI17C3), TrueMAB
인간 RRM1 단백질에 특이적인 단클론 항체로, IHC(P)에서 1:150 희석 비율로 검증됨. E.coli에서 발현된 인간 RRM1(aa 541-792) 단백질을 면역원으로 제작. 동결건조 형태로 제공되며, PBS(pH 7.3, 8% 트레할로스) 용액에 재구성 가능. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI17C3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 541–792 of human RRM1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits of ribonucleoside-diphosphate reductase, an enzyme essential for the biosynthesis of deoxyribonucleotides from ribonucleotides. It provides precursors for DNA synthesis and is implicated in carcinogenesis and tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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