Thermo Fisher Scientific AMACR/p504S (Prostate Cancer Marker) Polyclonal Antibody
AMACR/p504S 단백질을 표적하는 Rabbit Polyclonal Antibody로, 전립선암 관련 연구용으로 사용됩니다. Western Blot 및 Immunohistochemistry에 적합하며, Human 시료 반응성이 있습니다. 고순도 Protein A 정제, PBS buffer 기반으로 안정적 보관이 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50–1:100 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human AMACR protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme involved in the β-oxidation of branched-chain fatty acids. High expression of P504S protein is observed in prostatic adenocarcinoma but not in benign prostate tissue when analyzed by immunohistochemical staining of paraffin-embedded samples. Expression of P504S is also detected in premalignant prostate lesions such as high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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