Thermo Fisher Scientific TOR1AIP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TOR1AIP2. Recombinant protein control fragment (Product #RP-101459). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TOR1AIP2,uniProtId:Q8NFQ8-1,ncbiNodeId:9606,antigenRange:117-193,antigenLength:470,antigenImageFileName:PA5-62500_TOR1AIP2_Q8NFQ8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62500_TOR1AIP2_Q8NFQ8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648824

Product Specific Information

Immunogen sequence: PSHSPSDKVG RADAHLGSSS VALPKEASDG TGASQEPPTT DSQEAQSPGH SSAGQEGEDT LRRRLLAPEA GSHPQQT

Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 44%.

Target Information

One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.