Thermo Fisher Scientific 4EBP1 Polyclonal Antibody
4EBP1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 IHC(P) 검증 완료. 인간, 생쥐, 랫트 반응성. 고순도 항원 친화 크로마토그래피 정제, 액상 형태, 장기 보관 시 -20°C 권장.
- 카탈로그번호
- PA582838
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EIF4EBP1. Recombinant protein control fragment (Product #RP-93944) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789994 |
Product Specific Information
Immunogen sequence:
PGGTRIIYDR KFLMECRNSP VTKTPPRDLP TIPGVTSPSS DEPPMEASQS HLRNSPEDKR AGGEESQFEM DI
Target Information
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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