Thermo Fisher Scientific INTU Polyclonal Antibody
Thermo Fisher Scientific의 INTU 폴리클로날 항체는 인간 단백질 INTU를 인식하며, Western blot에 최적화되어 있습니다. 친화 크로마토그래피로 정제된 고순도 항체로, PBS와 자당 완충액에 보관됩니다. 섬모 형성과 세포 극성 연구에 적합합니다.
- 판매단위
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Applications
- Western Blot (WB): Tested at 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human INTU |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690064 |
Product Specific Information
This target displays homology in the following species:
- Dog: 79%
- Human: 100%
Target Information
INTU plays a key role in ciliogenesis and embryonic development. It regulates cilia formation by organizing the apical actin cytoskeleton and positioning basal bodies at the apical cell surface, which is essential for proper orientation of elongating ciliary microtubules. It also contributes to cell polarity through its role in ciliogenesis and indirectly affects hedgehog signaling. Proposed as a core component of the CPLANE (ciliogenesis and planar polarity effectors) complex that recruits peripheral IFT-A proteins to basal bodies (PubMed:27158779). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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