Thermo Fisher Scientific SNRPA1 Polyclonal Antibody
Human SNRPA1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관. 세포 분열 및 전사 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SNRPA1. Recombinant protein control fragment (Product #RP-99044) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647695 |
Product Specific Information
Immunogen sequence:
VTNKKHYRLY VIYKVPQVRV LDFQKVKLKE RQEAEKMFKG KRGAQLAKDI ARRSKTFNPG AGLPTDKKKG GPSP
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
SNRPA1 (U2 snRNP-A) is located in gene map locus 15q26.3 and is a 28 kDa protein. It is a specific component of the U2 snRNP particle and consists of a unique N-terminal leucine-rich region and an extremely hydrophobic RNA-binding C-terminal region.
It lacks segments homologous to RNP1 and RNP2 motifs found in several RNA-binding proteins.
SNRPA1 associates with U2 snRNP and participates in transcription and pre-mRNA splicing, potentially playing an important role in cell division and proliferation.
Patients with connective tissue disorders often produce autoantibodies against snRNP particles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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