Thermo Fisher Scientific FMO2 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
• Predicted reactivity: Mouse (83%), Rat (82%), Rabbit (84%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (81%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The flavin-containing monooxygenases (FMOs) are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, FMO2 catalyzes the N-oxidation of primary alkylamines through an N-hydroxylamine intermediate. In humans, this enzyme is truncated and likely rapidly degraded, resulting in no catalytic activity. A functional allele has been reported in African Americans, though no sequence evidence is available. The FMO2 gene is clustered with FMO1, FMO3, and FMO4 on chromosome 1.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.