Thermo Fisher Scientific FMO2 Polyclonal Antibody
FMO2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간에 반응하고 예측 반응종으로 마우스, 랫, 원숭이 등이 포함됩니다. 연구용으로만 사용 가능합니다.
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- PA522068
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 74–354 of FMO2 (Uniprot ID: Q99518) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152110 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (83%), Rat (82%), Rabbit (84%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (81%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The flavin-containing monooxygenases (FMOs) are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, FMO2 catalyzes the N-oxidation of primary alkylamines through an N-hydroxylamine intermediate. In humans, this enzyme is truncated and likely rapidly degraded, resulting in no catalytic activity. A functional allele has been reported in African Americans, though no sequence evidence is available. The FMO2 gene is clustered with FMO1, FMO3, and FMO4 on chromosome 1.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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