Thermo Fisher Scientific Human TSLP Synthetic Peptide
인간 TSLP 단백질의 C-말단 19개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 차단 실험 등에 사용 가능. 정제된 액상 형태로 제공되며 PBS 버퍼에 0.1% BSA와 0.02% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific Human TSLP Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
This peptide corresponds to 19 amino acids near the carboxy terminus of human TSLP.
PEP-0439 can be used as a blocking peptide with polyclonal antibody PA5-20319.
Target Information
TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain.
It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c(+) dendritic cells, naive CD4(+), and CD8(+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation.
TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4(+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis.
It is expressed in heart, liver, and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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