Thermo Fisher Scientific EpCAM/CD326 (Epithelial Marker) Recombinant Rabbit Monoclonal Antibody (EGP40/8130R)
EpCAM/CD326 표적의 재조합 토끼 단클론 항체로, 인간 시료에 반응합니다. 파라핀 포매 및 PFA 고정 조직의 면역조직화학(IHC)에 적합합니다. HEK293 세포에서 발현되었으며, Protein A로 정제된 액상 형태로 제공됩니다. 4°C에서 보관하며, 연구용으로만 사용 가능합니다.
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- 4072-RBM36-Px (2개 옵션)
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific EpCAM/CD326 (Epithelial Marker) Recombinant Rabbit Monoclonal Antibody (EGP40/8130R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | EGP40/8130R |
| Immunogen | Recombinant human EpCAM fragment from extracellular domain (around aa100–224) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ep-CAM (Epithelial Cell Adhesion Molecule, also known as ESA) is a transmembrane glycoprotein (~40 kDa) expressed in epithelial tissues. It functions as a calcium-independent homotypic adhesion molecule and influences cell cycle, proliferation, and metabolism by inducing genes such as c-myc, cyclin A, and cyclin E.
Ep-CAM overexpression is associated with enhanced epithelial proliferation and is highly expressed in human carcinomas, serving as a marker for tumors of epithelial lineage. It is localized on the baso-lateral surface of most simple epithelia and various carcinoma types, and can help distinguish adenocarcinomas from pleural mesotheliomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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