Thermo Fisher Scientific PNUTS Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:5,000

Immunoprecipitation (IP)

• Tested Dilution: 1–10 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Pig, Monkey, and Chimpanzee

Target Information

RNA polymerases transcribe nuclear genes for ribosomal RNA, representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA.
Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, suggesting that multiple signaling pathways are involved in Pol I transcription.
RPA40 and RPA16 are subunits of Pol I that associate at an early stage of assembly. RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).
RPA40, RPA16, and RPA135 encode the three subunits of RNA polymerase I, respectively. RPA194 is the largest subunit of RNA Pol I and is not a component of Pol II or Pol III.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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