
Thermo Fisher Scientific PNUTS Polyclonal Antibody
Thermo Fisher Scientific의 PNUTS Polyclonal Antibody는 Rabbit IgG 기반의 액상 비결합 항체로, Western blot과 Immunoprecipitation에 적합합니다. 인간 PPP1R10 단백질 C-말단 영역을 면역원으로 사용하며, 다양한 종에서 반응이 예측됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 1–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 900 and the C-terminus (residue 940) of Human Phosphatase Nuclear Targeting Subunit (PPP1R10, Protein Phosphatase 1 regulatory subunit 10) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Pig, Monkey, and Chimpanzee
Target Information
RNA polymerases transcribe nuclear genes for ribosomal RNA, representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes coding for large ribosomal RNA.
Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, suggesting involvement of multiple signaling pathways in Pol I transcription.
RPA40 and RPA16 are subunits of Pol I that associate early in RNA polymerase I assembly. RPA40 is essential for the function and integrity of the complex and is also a subunit of RNA polymerase III (Pol III).
RPA40, RPA16, and RPA135 encode the three subunits of RNA polymerase I, respectively. RPA194 is the largest subunit of RNA Pol I and is not a component of Pol II or Pol III.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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