Thermo Fisher Scientific ZMIZ2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 270-339. Recombinant protein control fragment (Product #RP-109798). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZMIZ2,uniProtId:Q8NF64-1,ncbiNodeId:9606,antigenRange:270-339,antigenLength:920,antigenImageFileName:PA5-145018_ZMIZ2_Q8NF64-1_Rabbit.svg,antigenImageFileNamePDP:PA5-145018_ZMIZ2_Q8NF64-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3091866

Product Specific Information

Immunogen sequence: SEVYPGQQYL QGGQYAPSTA QFAPSPGQPP APSPSYPGHR LPLQQGMTQS LSVPGPTGLH YKPTEQFNGQ

Antigen sequence identity: Mouse 86%; Rat 87%

Target Information

ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.