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Thermo Fisher Scientific PBR Polyclonal Antibody, FITC

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FITC로 표지된 PBR 폴리클로날 항체로, 사람과 랫드 시료에 반응합니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합하며, 친화 크로마토그래피로 정제되었습니다. 498/517 nm의 형광 특성을 가지며, -20°C 암소 보관이 필요합니다.

카탈로그번호: TSPO-FITC
브랜드: Thermo Fisher Scientific
카테고리: Polyclonal Antibodies
판매단위: pk

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마지막 업데이트 2025. 08. 04. 오후 02:33

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Thermo Fisher Scientific TSPO-FITC PBR Polyclonal Antibody, FITC 200 ul pk판매 단위 pk ·

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594,400원VAT 포함 653,840원

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Thermo Fisher Scientific · Thermo Fisher Scientific PBR Polyclonal Antibody, FITC

Applications and Tested Dilution

Application	Tested Dilution
Western Blot (WB)	1:500–1:1,000
Immunohistochemistry (IHC)	1:50–1:250
ELISA	1:10,000
Immunoprecipitation (IP)	1:50–1:250

Product Specifications

항목	내용
Species Reactivity	Human, Rat
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic peptide corresponding to a unique amino acid sequence on the 18 kDa mitochondrial benzodiazepine receptor protein
Conjugate	FITC
Excitation / Emission Max	498 / 517 nm
Form	Liquid
Concentration	0.5–1.5 mg/mL
Purification	Affinity chromatography
Storage Buffer	Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol
Contains	0.02% sodium azide
Storage Conditions	-20°C, store in dark
Shipping Conditions	Ambient (domestic); Wet ice (international)

Target Information

Mitochondrial peripheral-type benzodiazepine receptor (PBR) is an essential component of the steroidogenic machinery, mediating cholesterol delivery to the inner mitochondrial side chain cleavage cytochrome P-450 upon ligand activation.
PBR consists of three subunits: an isoquinoline binding site, a voltage-dependent anion channel, and an adenine nucleotide carrier. It is conserved from bacteria to humans and is widely expressed in peripheral organs, while in the brain it is primarily localized in glial cells.
Peroxisome proliferator perfluordecanoic acid (PFDA) inhibits Leydig cell steroidogenesis by affecting PBR mRNA stability, reducing PBR expression, cholesterol transport into mitochondria, and subsequent steroid formation.
A cytoplasmic protein, PRAX-1 (peripheral benzodiazepine receptor-associated protein 1), specifically interacts with PBR.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.