
Thermo Fisher Scientific OSCAR Polyclonal Antibody
Thermo Fisher Scientific의 OSCAR Polyclonal Antibody는 마우스 OSCAR 단백질을 인식하는 염소 유래 IgG 항체로, Western blot 및 IHC에 사용 가능. 골흡수세포 분화 연구에 적합하며, 항원 친화 크로마토그래피로 정제됨. -20°C 보관 필요.
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- PA547171
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse OSCAR Asp19–Asn228 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606397 |
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
A novel member of the leukocyte receptor complex (LRC) encoded family, OSCAR, is expressed specifically in osteoclasts (OC). OSCAR plays critical roles in regulating innate and adaptive immune responses and acts as a bone-specific regulator of osteoclast differentiation. Osteoclasts are multinucleated cells responsible for bone resorption and homeostasis. Unlike other LRC members, OSCAR expression is restricted to preosteoclasts and mature osteoclasts. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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