Thermo Fisher Scientific BCL6 Monoclonal Antibody (OTI11D8), TrueMAB
인간 BCL6 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western Blot에 적합. 고순도 친화 크로마토그래피 정제. PBS, 1% BSA, 50% 글리세롤 완충액에 보관. -20°C에서 보관하며 동결·해동 반복은 피해야 함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–300 of human BCL6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and Bcl-6 rearrangements have been detected in 33%–45% of diffuse large B cell lymphomas.
Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and in nodular, lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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