Thermo Fisher Scientific GLI2 Polyclonal Antibody
GLI2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 사용 가능. 인체 시료 반응성, 항원 친화 정제, 액상 형태로 제공. 4°C 보관, 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 950 to 1000 of human Zinc finger protein GLI2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are transcription factors that bind DNA through zinc finger motifs containing conserved H-C links. Gli family zinc finger proteins mediate Sonic hedgehog (Shh) signaling and act as potent oncogenes in embryonal carcinoma cells. The encoded protein localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression, playing a role during embryogenesis. It is associated with several phenotypes including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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