Thermo Fisher Scientific PAPPA Monoclonal Antibody (10E2)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

10E2

Immunogen

Purified human PAPP-A antigen.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

5.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2159348

Product Specific Information

MA1-22743 detects PAPP A in Human samples.

Target Information

Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down`s syndrome (trisomy 21).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.