Thermo Fisher Scientific PAPPA Monoclonal Antibody (10E2)
PAPP-A 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 ELISA에 사용 가능. 정제된 인간 PAPP-A 항원을 면역원으로 제작되었으며, Protein A로 정제된 액상 형태. 4°C에서 보관하며, 연구용으로만 사용 가능.
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- MA122743
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Applications
- Western Blot (WB): Assay-dependent
- ELISA: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10E2 |
| Immunogen | Purified human PAPP-A antigen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2159348 |
Product Specific Information
MA1-22743 detects PAPP-A in Human samples.
Target Information
Pregnancy-associated plasma protein-A (PAPP-A, also known as Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, first identified in serum from pregnant women.
The heterotetramer consists of two PAPP-A subunits and two proMBP subunits.
Low maternal serum levels of PAPP-A in first-trimester biochemical screening are used as a marker of Down’s syndrome (trisomy 21).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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