Thermo Fisher Scientific OLFM4 Polyclonal Antibody
Rabbit polyclonal antibody against human OLFM4 단백질로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% 글리세롤, 0.02% sodium azide) 용액 형태로 제공. 연구용으로만 사용 가능.
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- PA585041
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Immunocytochemistry (ICC/IF)
- Tested Dilution: Not specified
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human OLFM4 (Product # RP-108295) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792190 |
Product Specific Information
Immunogen sequence:
KLVIQLKESF GGSSEIVDQL EVEIRNMTLL VEKLETLDKN NVLAIRREIV ALKTKLKECE ASKDQNTPVV HPPPTPGSCG HGGVVN
Target Information
OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and is selectively expressed in inflamed colonic epithelium. It has one signal peptide, six N-linked glycosylation motifs, and forms disulfide-bonded multimers. OLFM4 may have a matrix-related function in differentiation and acts as an antiapoptotic factor by binding to GRIM-19. It is constitutively expressed in certain cancer cells and may serve as a diagnostic marker. OLFM4 also promotes proliferation of PANC-1 cells by facilitating transition from the S to G2/M phase and may mediate cell adhesion through interactions with lectins and cadherins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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