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Thermo Fisher Scientific DGKQ Polyclonal Antibody
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Thermo Fisher Scientific DGKQ Polyclonal Antibody

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Human DGKQ 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20~1:50 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 핵 내 DAG 신호 조절 연구에 적합.

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마지막 업데이트 2025. 07. 27. 오전 10:32
Thermo Fisher Scientific PA555422 DGKQ Polyclonal Antibody 100 ul pk판매 단위 pk
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773,300원VAT 포함 850,630원

Thermo Fisher Scientific · Thermo Fisher Scientific DGKQ Polyclonal Antibody

Applications

Tested Applications and Dilution

  • Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein corresponding to Human DGKQ. Recombinant protein control fragment (Product #RP-102422).
Conjugate Unconjugated
Form Liquid
Concentration 0.2 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice
RRID AB_2640552

Product Specific Information

Immunogen sequence:
HVSLFVGGLP PGLSPEEYSS LLHEAGATKA TVVSVSHIYS SQGAVVLDVA CFAEAERLYM LLKDMAVRGR LLTALVLPDL LHAKLPPDSC PLLVFVNPKS G

Highest antigen sequence identity to orthologs:

  • Mouse: 82%
  • Rat: 84%

Target Information

Diacylglycerol (DAG) is a fundamental lipid second messenger produced in the nucleus. The accumulation of DAG regulates cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, reducing protein kinase C activity and controlling T lymphocyte cell cycle progression.
DGK-theta is a Type V DGK that localizes mainly to the nucleus of various cell lines (MDA-MB-453, MCF-7, PC12, HeLa) and co-localizes with phosphatidylinositol 4,5-bisphosphate (PIP(2)). DGK-theta responds to alpha-Thrombin stimulation.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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