Thermo Fisher Scientific DMRT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DMRT1. Recombinant protein control fragment (Product #RP-100719). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DMRT1,uniProtId:Q9Y5R6-1,ncbiNodeId:9606,antigenRange:235-369,antigenLength:373,antigenImageFileName:PA5-55713_DMRT1_Q9Y5R6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55713_DMRT1_Q9Y5R6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640633

Product Specific Information

Immunogen sequence: LAADSASGEV GNPLGGSPVK NSLRGLPGPY VPGQTGNQWQ MKNMENRHAM SSQYRMHSYY PPPSYLGQSV PQFFTFEDAP SYPEARASVF SPPSSQDSGL VSLSSSSPIS NKSTKAVLEC EPASEPSSFT VTPVI

Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 78%.

Target Information

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.