Thermo Fisher Scientific DMRT1 Polyclonal Antibody
DMRT1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin)에 적용 가능. Human 반응성, Mouse에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, 0.2 mg/mL 농도의 액상 형태로 제공. 연구용 한정.
- 카탈로그번호
- PA555713
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- Publications: 1 publication available
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DMRT1. Recombinant protein control fragment (Product #RP-100719). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640633 |
Product Specific Information
Immunogen sequence:
LAADSASGEV GNPLGGSPVK NSLRGLPGPY VPGQTGNQWQ MKNMENRHAM SSQYRMHSYY PPPSYLGQSV PQFFTFEDAP SYPEARASVF SPPSSQDSGL VSLSSSSPIS NKSTKAVLEC EPASEPSSFT VTPVI
- Highest antigen sequence identity to orthologs:
- Mouse: 77%
- Rat: 78%
Target Information
This gene is found in a cluster with two other members of the gene family, sharing a zinc finger-like DNA-binding motif (DM domain).
The DM domain is a conserved component of the vertebrate sex-determining pathway and a key regulator of male development in flies and nematodes.
The gene exhibits a gonad-specific and sexually dimorphic expression pattern.
Defective testicular development and XY feminization occur when this gene is hemizygous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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