Thermo Fisher Scientific UBR2 Polyclonal Antibody
Human UBR2 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBR2. Recombinant protein control fragment (Product #RP-94602). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649205 |
Product Specific Information
Immunogen sequence:
QPNLTQWIRT ISQQIKALQF LRKEESTPNN ASTKNSENVD ELQLPEGFRP DFRPKIPYSE SIKEMLTTFG TATYKVGLKV HPN
Highest antigen sequence identity to the following orthologs:
- Mouse: 59%
- Rat: 65%
Target Information
The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1.
NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate.
Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1.
In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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