Thermo Fisher Scientific KCNQ2 Polyclonal Antibody
KCNQ2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. IHC, ICC, Flow Cytometry, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 1 mg/mL 농도의 액상 제품입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 3 µg |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human KCNQ2 (amino acids 91–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01 M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KCNQs are members of the voltage-dependent non-inactivating potassium channel family. There are five known KCNQs (KCNQ1–5) found in the central nervous system. KCNQ2 and KCNQ3 play key roles in M-current activation and form heteromultimers that significantly increase the M-current. Inhibition of M-current regulates neuronal excitability and synaptic responsiveness. Mutations in these proteins are associated with disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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