Thermo Fisher Scientific ArgRS/Arginyl tRNA synthetase Polyclonal Antibody
Thermo Fisher Scientific의 ArgRS/Arginyl tRNA synthetase 폴리클로날 항체는 인간, 마우스, 랫트 반응성을 가지며 WB, IHC, ICC, ELISA 등에 적합합니다. KLH 결합 합성 펩타이드(aa 401-500)를 면역원으로 사용하였으며, Protein A로 정제된 1 mg/mL 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ArgRS/Arginyl tRNA synthetase, amino acids 401–500 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family that includes LeuRS, ValRS, and IleRS. These enzymes catalyze the aminoacylation of tRNA by their cognate amino acid.
ArgRS localizes to the cytoplasm and exists as a monomer but can associate with other tRNA synthetases and auxiliary proteins to form a multisubunit complex. In the presence of ATP, arginine (Arg), and tRNA, ArgRS attaches Arg to tRNA(Arg) at its synthetic active site. Two cytoplasmic forms of ArgRS have been described in mammals, differing by the addition of a 73-amino-acid sequence required for assembly into the multisubunit complex.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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