Thermo Fisher Scientific TET3 Polyclonal Antibody
TET3 단백질에 특이적으로 반응하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, 고농도(70 mg/mL) 액상 형태로 제공. -20°C에서 안정적으로 보관 가능하며 연구용으로 사용.
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Thermo Fisher Scientific TET3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| ELISA | 1:50,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TET3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a human TET-3 domain containing the N-terminal 160 amino acids of the protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 70 mg/mL |
| Storage Buffer | 0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
- Directed against and shows specific reactivity for Tet3 protein.
- Cross-reactivity with Tet1 and Tet2 has not been determined.
Target Information
TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells.
Unlike the related TET2 protein, mutations in TET3 have not been observed in myeloid malignancies.
TET3 is involved in the demethylation of zygotic DNA before the first mitosis and plays a role in epigenetic reprogramming of paternal DNA following fertilization. It may also contribute to somatic cell nuclear reprogramming during animal cloning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 100-401-N94_TET3_O43151-1_Rabbit.svg, 100-401-N94_TET3_O43151-1_Rabbit_PDP.jpeg)
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