Thermo Fisher Scientific PC4 Polyclonal Antibody
Rabbit polyclonal antibody against human PC4, suitable for WB and IHC(P). Provides high specificity and reactivity across multiple species. Supplied as a liquid at 1 mg/mL, stored at 4°C short term or -20°C long term. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human PC4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2121824 |
Product Specific Information
- Recommended positive control: HepG2
- Predicted reactivity: Cow (100%), Dog (100%), Mouse (100%), Rat (100%), Yeast (91%), Zebrafish (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator with the ability to suppress promoter-driven as well as nonspecific transcription via its DNA-binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH, which protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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