Thermo Fisher Scientific JAKMIP1 Polyclonal Antibody
JAKMIP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료에 반응하며 Western blot에 적합. 액상 형태, 0.5 mg/mL 농도, PBS(2% sucrose) 저장. -20°C 보관, 동결/해동 반복 피함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human JAKMIP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605992 |
Product Specific Information
Peptide Sequence:
FLRLQVLEQQ HVIDDLSLER ERLLRSKRHR GKSLKPPKKH VVETFFGFDE
Sequence Homology:
Cow: 92%
Dog: 100%
Guinea Pig: 93%
Horse: 100%
Human: 100%
Mouse: 100%
Pig: 100%
Rat: 100%
Target Information
JAKMIP1 (also known as Marlin-1) is a highly conserved vertebrate-specific microtubule-associated protein involved in JAK1 signaling and microtubule cytoskeleton rearrangements. It is predominantly expressed in neuronal and lymphoid cells and colocalizes with microtubules.
Multiple isoforms exist:
- Isoforms 1 and 5 are expressed in liver, lung, and skeletal muscle.
- Isoforms 2–4 are specifically expressed in brain and retina.
JAKMIP1 participates in polarized secretion in lymphocytes and may act as a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 expression is associated with genetic conditions linked to autism in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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