Thermo Fisher Scientific PHGDH Polyclonal Antibody
Thermo Fisher Scientific의 PHGDH Polyclonal Antibody는 인간 PHGDH 단백질을 인식하는 토끼 다클론 항체입니다. Western blot, IHC, Flow cytometry에 적합하며, 고순도의 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Flow Cytometry (Flow) | 1:10–1:50 | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 249–277 amino acids from the central region of human PHGDH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2542133 |
Product Specific Information
This antibody is predicted to react with mouse, non-human primate, and rat based on sequence homology.
Target Information
The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is essential for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been associated with congenital microcephaly, psychomotor retardation, and other symptoms. Multiple alternatively spliced transcript variants have been identified, though the full-length nature of most is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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