Thermo Fisher Scientific ORAI3 Polyclonal Antibody
인간 ORAI3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 4°C 또는 -20°C 보관 가능.
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Thermo Fisher Scientific ORAI3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ORAI3. Recombinant protein control fragment (Product #RP-91115). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789676 |
Product Specific Information
Immunogen sequence:
APLDTPTPMV PTSRVPGTLA PVATSLSPAS NLPRSSASAA PSQAEPACPP RQACGGGGAH GPGWQA
Target Information
ORAI3 is a protein coding gene involved in calcium signaling and regulation of calcium homeostasis. It is a member of the ORAI family that forms calcium release-activated calcium (CRAC) channels in the plasma membrane. These channels are activated by calcium depletion from the endoplasmic reticulum, leading to an influx of calcium ions into the cytoplasm.
ORAI3 is implicated in T-cell activation, muscle contraction, and neurotransmitter release. Dysregulation of ORAI3 expression or function is associated with immune disorders, cancer, and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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