Thermo Fisher Scientific BAF57 Polyclonal Antibody
BAF57 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용 가능. Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 4°C 단기 저장 및 -20°C 장기 보관 권장.
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Thermo Fisher Scientific BAF57 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 349–411 of Human BAF57 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545897 |
Product Specific Information
- Recommended positive control: Raji
- Predicted reactivity: Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The BAF57 protein is part of the ATP-dependent chromatin remodeling complex SWI/SNF, essential for transcriptional activation of genes repressed by chromatin. It binds to 4-way junction DNA, mimicking nucleosome entry/exit topology. The protein includes a DNA-binding HMG domain; however, disruption of this domain does not abolish DNA-binding or nucleosome-displacement activities. Unlike most SWI/SNF proteins, BAF57 has no yeast counterpart.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-28421_BAF57_Q969G3-1_Rabbit.svg, PA5-28421_BAF57_Q969G3-1_Rabbit_PDP.jpeg)
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