Thermo Fisher Scientific IL-1 beta Polyclonal Antibody
IL-1 beta 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, 인간, 생쥐, 랫트 반응성을 갖습니다. 고순도 Affinity Chromatography 정제, 액상 형태로 안정적인 저장이 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IL-1 beta Polyclonal Antibody
Thermo Fisher Scientific IL-1 beta Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–269 of human IL1β (NP_0005671) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.34 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804633 |
Product Specific Information
Immunogen sequence:
MAEVPELASE MMAYYSGNED DLFFEADGPK QMKCSFQDLD LCPLDGGIQL RISDHHYSKG FRQAASVVVA MDKLRKMLVP CPQTFQENDL STFFPFIFEE EPIFFDTWDN EAYVHDAPVR SLNCTLRDSQ QKSLVMSGPY ELKALHLQGQ DMEQQVVFSM SFVQGEESND KIPVALGLKE KNLYLSCVLK DDKPTLQLES VDPKNYPKKK MEKRFVFNKI EINNKLEFES AQFPNWYIST SQAENMPVFL GGTKGGQDIT DFTMQFVSS
Positive Samples: Mouse liver
Cellular Location: Cytoplasm, Cytoplasmic vesicle, Lysosome, Autophagosome, Cytosol, Exosome
Target Information
Interleukin-1 beta (IL-1β) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. It is synthesized as a 31 kDa inactive pro-form that accumulates in the cytosol and is cleaved into the active 17 kDa protein upon inflammasome activation. IL-1β lacks a classical signal peptide and is secreted via a noncanonical mechanism. It binds IL-1RI and IL-1RII receptors, shared with IL-1α, and its activity is regulated by IL-1 Receptor Antagonist (IL-1RA). IL-1β plays a key role in innate immune responses and inflammation, with elevated levels linked to chronic inflammatory diseases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.