Thermo Fisher Scientific GTF2IRD1 Polyclonal Antibody
GTF2IRD1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
- 카탈로그번호
- PA549893
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from N-terminal of human GTF2IRD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635346 |
Product Specific Information
This antibody detects endogenous levels of total GTF2IRD1 protein.
Target Information
Williams-Beuren syndrome (WBS) is a developmental disorder caused by a hemizygous microdeletion on chromosome 7q11.23. It is characterized by physical, cognitive, and behavioral traits such as facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies, and neurologic abnormalities. The WBSCR11 gene, also known as GTF2IRD1, is located within the WBS deletion region and may contribute to the developmental symptoms of WBS due to loss of the encoded transcription factor. WBSCR11 is expressed in all adult tissues and shows distinct spatial and temporal expression during embryogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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