Thermo Fisher Scientific NECTIN1/CD111/PVRL1 Polyclonal Antibody
Rabbit polyclonal antibody targeting NECTIN1/CD111/PVRL1 for WB and IP applications. Recognizes antigen region 225–275 of human Nectin 1. Supplied as unconjugated liquid at 1 mg/mL. Stored at 4°C, shipped on wet ice. For research use only.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 225–275 of human Nectin 1 (UniProt ID: Q15223-1, antigen length: 517 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells. The protein is a calcium-independent cell-cell adhesion molecule belonging to the immunoglobulin superfamily, featuring:
- 3 extracellular immunoglobulin-like loops
- A single transmembrane domain
- A cytoplasmic region
It functions as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells.
Mutations in this gene are associated with cleft lip and palate/ectodermal dysplasia 1 syndrome and non-syndromic cleft lip with or without cleft palate.
Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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