Thermo Fisher Scientific GADD45GIP1/CRIF1 Polyclonal Antibody
GADD45GIP1/CRIF1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며 인간과 생쥐 반응성. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 제품으로 연구용에 적합.
- 카탈로그번호
- A305163A
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150–200 of human Growth arrest and DNA damage-inducible proteins-interacting protein 1 (GADD45GIP1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase essential for the NF-kappa-B signaling pathway, activated by various stimuli such as inflammatory cytokines, bacterial or viral products, DNA damage, and other cellular stresses.
IKK beta phosphorylates inhibitors of NF-kappa-B on critical serine residues, leading to polyubiquitination and proteasomal degradation. This allows NF-kappa-B to translocate into the nucleus and activate transcription of genes involved in immune response, growth control, and protection against apoptosis.
Mutations in the IKK beta gene can result in Immunodeficiency 15 (IMD15).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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