Thermo Fisher Scientific YAP1 Polyclonal Antibody
YAP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간을 포함한 다양한 종에서 반응 예측. IHC 및 IHC(Paraffin) 응용에 적합하며, 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 350 and 400 of Human Yes-associated protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Sheep, Bovine, Dog, Horse, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Naked mole rat, and Small-eared galago.
Target Information
YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, functioning as a transcriptional co-activator and oncogene. It is transcriptionally activated in squamous cell carcinoma cells and acts as both coactivator and corepressor. YAP is a critical downstream regulatory target in the Hippo signaling pathway, which controls organ size and tumor suppression by limiting proliferation and promoting apoptosis. It also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and migration. Mutations in the IRF5 gene result in coloboma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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