Thermo Fisher Scientific RPLP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human RPLP1(Accession P05386), corresponding to amino acid residues G36-A86. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RPLP1,uniProtId:P05386-1,ncbiNodeId:9606,antigenRange:36-86,antigenLength:114,antigenImageFileName:PA5-103540_RPLP1_P05386-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103540_RPLP1_P05386-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2852876

Product Specific Information

Antibody detects endogenous levels of total RPLP1.

Target Information

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein LP1 (ribosomal protein, large, P1), also known as 60S acidic ribosomal protein P1, RPP1 or RPLP1, is a 114 amino acid acidic protein that belongs to the ribosomal protein L12P family. A key component during the elongation step of protein synthesis, Ribosomal Protein LP1 forms a pentameric complex (in conjunction with LP2 and LP0) that regulates ribosome assembly and plays a role in translation initiation. Like other mammalian ribosomal proteins, Ribosomal Protein LP1 exists as multiple processed pseudogenes that are found throughout the genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.