Thermo Fisher Scientific TIMP1 Monoclonal Antibody (102D1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

View 8 publications 8 publications

Immunohistochemistry (IHC)

-

View 26 publications 26 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:250

-

Neutralization (Neu)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

102D1

Immunogen

Recombinant human TIMP-1.

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• Biotin
• Request custom conjugation

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C

RRID

AB_417075

Product Specific Information

MS608PABX targets TIMP-1 in immunohistochemistry and western blot applications and shows reactivity with human samples.

The MS608PABX immunogen is recombinant human TIMP-1.

MS608PABX detects TIMP-1 which has a predicted molecular weight of approximately 21 kDa.

Target Information

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.