Thermo Fisher Scientific TIMP1 Monoclonal Antibody (102D1)
인간 TIMP-1 단백질을 표적으로 하는 단클론 항체. Western blot, IHC, ICC 등 다양한 응용에 적합. 단백질 G로 정제된 액상 형태로 제공되며, PBS(pH 7.4)에 보존제 없이 저장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | View 8 publications |
| Immunohistochemistry (IHC) | - | View 26 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:250 | - |
| Neutralization (Neu) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 102D1 |
| Immunogen | Recombinant human TIMP-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C |
| RRID | AB_417075 |
Additional Formats
Product Specific Information
MS608PABX targets TIMP-1 in immunohistochemistry and western blot applications and shows reactivity with human samples.
The immunogen is recombinant human TIMP-1.
MS608PABX detects TIMP-1 with a predicted molecular weight of approximately 21 kDa.
Target Information
TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that forms one-to-one complexes with target metalloproteinases (e.g., collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16.
It also functions as a growth factor regulating cell differentiation, migration, and apoptosis, and activates cellular signaling cascades via CD63 and ITGB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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