
Thermo Fisher Scientific AFMID Polyclonal Antibody
Rabbit polyclonal antibody against human AFMID. Validated for IHC (P) and ICC/IF. Recognizes recombinant AFMID protein. Suitable for research use in tryptophan metabolism and kynurenine pathway studies.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AFMID. Recombinant protein control fragment (Product # RP-93517) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637748 |
Product Specific Information
Immunogen sequence:
VSGVGFPSKV PWKKMSAEEL ENQYCPSRWV VRLGAEEALR TYSQIGIEAT TRARATRKSL LHVPYGD
Highest antigen sequence identity to the following orthologs:
- Mouse: 49%
- Rat: 48%
Target Information
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
Kynurenine may be further oxidized to nicotinic acid, NAD(H), and NADP(H).
Required for elimination of toxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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