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Thermo Fisher Scientific Occludin Monoclonal Antibody (OC-3F10), FITC

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FITC 결합된 Occludin 단클론 항체로, 세포 간 밀착연접 단백질 분석에 적합합니다. WB, IHC, ICC/IF, Flow Cytometry 등에 사용 가능하며, 다양한 종에 반응합니다. 단백질 A로 정제된 고순도 항체로 안정적인 형광 검출을 제공합니다.

카탈로그번호: 331511
브랜드: Thermo Fisher Scientific
카테고리: Monoclonal Antibodies
판매단위: pk

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Thermo Fisher Scientific 331511 Occludin Monoclonal Antibody (OC-3F10), FITC 100 ug pk판매 단위 pk ·

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764,500원VAT 포함 840,950원

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Thermo Fisher Scientific · Thermo Fisher Scientific Occludin Monoclonal Antibody (OC-3F10), FITC

Thermo Fisher Scientific Occludin Monoclonal Antibody (OC-3F10), FITC

Applications and Tested Dilution

Application	Tested Dilution	Publications
Western Blot (WB)	-	View 2 publications
Immunohistochemistry (IHC)	-	View 2 publications
Immunocytochemistry (ICC/IF)	5 µg/mL	View 6 publications
Flow Cytometry (Flow)	-	View 1 publication

Product Specifications

Property	Description
Species Reactivity	Dog, Human, Mouse, Rat
Published Species	Human, Mouse, Non-human primate, Rabbit, Rat
Host / Isotype	Mouse / IgG1, kappa
Class	Monoclonal
Type	Antibody
Clone	OC-3F10
Immunogen	GST fusion protein consisting of the C-terminal region (~150aa) of human occludin
Conjugate	FITC
Excitation / Emission Max	498 / 517 nm
Form	Liquid
Concentration	0.5 mg/mL
Purification	Protein A
Storage Buffer	PBS, pH 7.4, with 50% glycerol, 1% BSA
Contains	0.1% sodium azide
Storage Conditions	4°C, store in dark
Shipping Conditions	Ambient (domestic); Wet ice (international)
RRID	AB_2533102

Additional Formats

Unconjugated
Alexa Fluor 488
Alexa Fluor 594
HRP
Request custom conjugation

Target Information

Occludin is a 65 kDa protein that can exist in various phosphorylated forms (up to ~82 kDa). It plays a key role in regulating tight junction localization and function. Polyunsaturated fatty acids up-regulate occludin expression, enhancing transendothelial resistance and reducing permeability. Expression levels vary by tissue—high in brain tissue and lower in non-neural tissues. Structural features are highly conserved across species. Under-expression of occludin contributes to tumor endothelial junction permeability and brain tumor edema formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.