
Thermo Fisher Scientific HLA Class 1 ABC (MHC I) Recombinant Rabbit Monoclonal Antibody (MHC-I/8147R)
HLA Class I (ABC, MHC I) 항원을 인식하는 Thermo Fisher Scientific의 재조합 토끼 모노클로날 항체. 인간 시료 반응성, IHC(P) 및 IHC(PFA) 적용 가능. 고순도 Protein A/G 정제, PBS buffer, 무보존제. 면역펩티도믹스 및 항바이러스·항종양 연구에 적합.
- 카탈로그번호
- RBM3-8147-P1ABX
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MHC-I/8147R |
| Immunogen | Recombinant fragment (around aa100–300) of human HLA-I protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus playing a key role in anti-viral and anti-tumor defense.
Human HLA-class I antigens are represented by HLA-A, HLA-B, and HLA-C molecules.
HLA and MHC antibodies are significant in Immunopeptidomics, enabling the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: RBM3-8147-P1ABX_HLA-ABC_P04439-1_Rabbit.svg, RBM3-8147-P1ABX_HLA-ABC_P01889-1_Rabbit.svg, RBM3-8147-P1ABX_HLA-ABC_P10321-1_Rabbit.svg)
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