Thermo Fisher Scientific PDCD2 Polyclonal Antibody
Human PDCD2 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 세포주기 조절 관련 연구에 적합. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human PDCD2. Recombinant protein control fragment (Product #RP-108051) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2857143 |
Product Specific Information
Immunogen sequence:
PLSFLLQVYA PLPGRPDAFH RCIFLFCCRE QPCCAGLRVF RNQLPRKNDF YSYEPPSENP PPETGESVCL QLKSGA
Target Information
Essential component of an SCF-type E3 ligase complex, SCF(NIPA), which controls mitotic entry by mediating ubiquitination and degradation of cyclin B1 (CCNB1).
Phosphorylation regulates SCF(NIPA) assembly, restricting CCNB1 ubiquitination to interphase.
Inactivation leads to nuclear accumulation of CCNB1 and premature mitotic entry.
May have an antiapoptotic role in NPM-ALK-mediated signaling events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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