Thermo Fisher Scientific DDX18 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DDX18 protein. Validated for WB and ICC/IF applications. Purified by antigen affinity chromatography and supplied in PBS with glycerol. Suitable for research use in RNA helicase and Myc/Max pathway studies.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human DDX18. Recombinant protein control fragment (Product #RP-105997). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664947 |
Product Specific Information
Immunogen sequence:
ETMGSRKVKKS KQKPMNVGLS ETQNGGMSQE AVGNIKVTKS PQKSTVLTNG EAAMQSSNSE S
Highest antigen sequence identity to the following orthologs:
- Mouse: 45%
- Rat: 42%
Target Information
ATP-dependent RNA helicase DDX18 belongs to the DEAD box helicase family, which contains one helicase ATP-binding domain and one helicase C-terminal domain. DDX18 is induced by Myc and Max and is involved in splicing and nuclear export. It is reported to be differentially expressed during viral latency and at early times after induction into active replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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