Thermo Fisher Scientific RAB7A Polyclonal Antibody
RAB7A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot과 IHC에 사용 가능. 인간 및 마우스 반응성, 고순도 항원 친화 크로마토그래피 정제. 액상 형태로 안정적이며 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human RAB7A (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736493 |
Product Specific Information
- Positive Control: 293T, A431, HeLa, HepG2
- Predicted Reactivity: Rat (99%), Xenopus laevis (95%), Dog (100%), Rabbit (97%), Sheep (99%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RAB family members are small, RAS-related GTP-binding proteins that regulate vesicular transport. Each RAB protein interacts with multiple proteins involved in exocytic and endocytic pathways.
RAB7A regulates vesicle traffic in late endosomes and lysosomes and is implicated in cellular vacuolation induced by Helicobacter pylori VacA cytotoxin.
Mutations in conserved residues of this gene have been associated with Charcot-Marie-Tooth (CMT) type 2 neuropathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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