Thermo Fisher Scientific KRT19 Monoclonal Antibody (OTI8D1), TrueMAB
인간 KRT19 단백질을 인식하는 단일클론 항체로, Western blot과 면역조직화학(IHC)에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 세포 분화 및 상피세포 마커 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 240–390 of human KRT19 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cytokeratin 19 is a member of the intermediate filament protein family, exhibiting biochemical diversity across human epithelial tissues. Human cytokeratins (1–20) vary in molecular weight (40–68 kDa) and isoelectric point (pH 4.9–7.8).
Cytokeratin subtype expression patterns are useful for distinguishing epithelial malignancies and assessing tissue differentiation. Cytokeratin 19 is not expressed in hepatocytes, making it a valuable marker for identifying liver metastasis in diagnostic research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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